GO Term |
Description |
P-value |
Enrichment (N, B, n, b) |
Genes |
GO:0008139 |
nuclear localization sequence binding |
3.5E-4 |
33.26 (17361,9,174,3) |
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NFKBIA - nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, alpha
TNPO2 - transportin 2
KPNA2 - karyopherin alpha 2 (rag cohort 1, importin alpha 1)
|
GO:0005048 |
signal sequence binding |
4.13E-4 |
18.14 (17361,22,174,4) |
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KCNIP2 - kv channel interacting protein 2
NFKBIA - nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, alpha
TNPO2 - transportin 2
KPNA2 - karyopherin alpha 2 (rag cohort 1, importin alpha 1)
|
GO:0022834 |
ligand-gated channel activity |
4.54E-4 |
2.01 (17361,128,2026,30) |
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KCNJ1 - potassium inwardly-rectifying channel, subfamily j, member 1
HTR3C - 5-hydroxytryptamine (serotonin) receptor 3, family member c
KCNJ5 - potassium inwardly-rectifying channel, subfamily j, member 5
KCNJ8 - potassium inwardly-rectifying channel, subfamily j, member 8
KCNJ10 - potassium inwardly-rectifying channel, subfamily j, member 10
KCNJ11 - potassium inwardly-rectifying channel, subfamily j, member 11
P2RX2 - purinergic receptor p2x, ligand-gated ion channel, 2
GLRB - glycine receptor, beta
GLRA1 - glycine receptor, alpha 1
TRPC6 - transient receptor potential cation channel, subfamily c, member 6
GRIN1 - glutamate receptor, ionotropic, n-methyl d-aspartate 1
CHRNA6 - cholinergic receptor, nicotinic, alpha 6
GRIN3B - glutamate receptor, ionotropic, n-methyl-d-aspartate 3b
SHROOM2 - shroom family member 2
GRIN2A - glutamate receptor, ionotropic, n-methyl d-aspartate 2a
GRIA1 - glutamate receptor, ionotropic, ampa 1
CHRNB2 - cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 - cholinergic receptor, nicotinic, beta 3
GRID1 - glutamate receptor, ionotropic, delta 1
GRIA4 - glutamate receptor, ionotrophic, ampa 4
GLRA4 - glycine receptor, alpha 4
CHRNA3 - cholinergic receptor, nicotinic, alpha 3
KCNJ15 - potassium inwardly-rectifying channel, subfamily j, member 15
SCNN1G - sodium channel, nonvoltage-gated 1, gamma
ORAI1 - orai calcium release-activated calcium modulator 1
ACCN3 - amiloride-sensitive cation channel 3
RYR3 - ryanodine receptor 3
GRIN2D - glutamate receptor, ionotropic, n-methyl d-aspartate 2d
CHRNA10 - cholinergic receptor, nicotinic, alpha 10
TRPC4 - transient receptor potential cation channel, subfamily c, member 4
|
GO:0015276 |
ligand-gated ion channel activity |
4.54E-4 |
2.01 (17361,128,2026,30) |
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KCNJ1 - potassium inwardly-rectifying channel, subfamily j, member 1
HTR3C - 5-hydroxytryptamine (serotonin) receptor 3, family member c
KCNJ5 - potassium inwardly-rectifying channel, subfamily j, member 5
KCNJ8 - potassium inwardly-rectifying channel, subfamily j, member 8
KCNJ10 - potassium inwardly-rectifying channel, subfamily j, member 10
KCNJ11 - potassium inwardly-rectifying channel, subfamily j, member 11
P2RX2 - purinergic receptor p2x, ligand-gated ion channel, 2
GLRB - glycine receptor, beta
GLRA1 - glycine receptor, alpha 1
TRPC6 - transient receptor potential cation channel, subfamily c, member 6
CHRNA6 - cholinergic receptor, nicotinic, alpha 6
GRIN1 - glutamate receptor, ionotropic, n-methyl d-aspartate 1
GRIN3B - glutamate receptor, ionotropic, n-methyl-d-aspartate 3b
GRIN2A - glutamate receptor, ionotropic, n-methyl d-aspartate 2a
SHROOM2 - shroom family member 2
GRIA1 - glutamate receptor, ionotropic, ampa 1
CHRNB2 - cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 - cholinergic receptor, nicotinic, beta 3
GRID1 - glutamate receptor, ionotropic, delta 1
GRIA4 - glutamate receptor, ionotrophic, ampa 4
GLRA4 - glycine receptor, alpha 4
CHRNA3 - cholinergic receptor, nicotinic, alpha 3
KCNJ15 - potassium inwardly-rectifying channel, subfamily j, member 15
SCNN1G - sodium channel, nonvoltage-gated 1, gamma
ORAI1 - orai calcium release-activated calcium modulator 1
ACCN3 - amiloride-sensitive cation channel 3
RYR3 - ryanodine receptor 3
GRIN2D - glutamate receptor, ionotropic, n-methyl d-aspartate 2d
CHRNA10 - cholinergic receptor, nicotinic, alpha 10
TRPC4 - transient receptor potential cation channel, subfamily c, member 4
|
GO:0004252 |
serine-type endopeptidase activity |
4.96E-4 |
15.65 (17361,153,29,4) |
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KLK7 - kallikrein-related peptidase 7
KLK8 - kallikrein-related peptidase 8
KLK5 - kallikrein-related peptidase 5
KLK10 - kallikrein-related peptidase 10
|
GO:0047173 |
phosphatidylcholine-retinol O-acyltransferase activity |
5.76E-4 |
1,736.10 (17361,1,10,1) |
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LRAT - lecithin retinol acyltransferase (phosphatidylcholine--retinol o-acyltransferase)
|
GO:0005231 |
excitatory extracellular ligand-gated ion channel activity |
7.25E-4 |
3.92 (17361,49,994,11) |
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CHRNA3 - cholinergic receptor, nicotinic, alpha 3
GRIN1 - glutamate receptor, ionotropic, n-methyl d-aspartate 1
GRIN3B - glutamate receptor, ionotropic, n-methyl-d-aspartate 3b
GRIN2A - glutamate receptor, ionotropic, n-methyl d-aspartate 2a
GRIA1 - glutamate receptor, ionotropic, ampa 1
GRIN2D - glutamate receptor, ionotropic, n-methyl d-aspartate 2d
P2RX2 - purinergic receptor p2x, ligand-gated ion channel, 2
GLRB - glycine receptor, beta
CHRNB2 - cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB3 - cholinergic receptor, nicotinic, beta 3
GLRA1 - glycine receptor, alpha 1
|
GO:0016595 |
glutamate binding |
7.75E-4 |
11.06 (17361,7,897,4) |
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GRIN1 - glutamate receptor, ionotropic, n-methyl d-aspartate 1
GRIN2A - glutamate receptor, ionotropic, n-methyl d-aspartate 2a
GRIN2D - glutamate receptor, ionotropic, n-methyl d-aspartate 2d
SLC1A1 - solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system xag), member 1
|
GO:0008236 |
serine-type peptidase activity |
7.84E-4 |
13.84 (17361,173,29,4) |
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KLK7 - kallikrein-related peptidase 7
KLK8 - kallikrein-related peptidase 8
KLK5 - kallikrein-related peptidase 5
KLK10 - kallikrein-related peptidase 10
|
GO:0017171 |
serine hydrolase activity |
8.4E-4 |
13.61 (17361,176,29,4) |
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KLK7 - kallikrein-related peptidase 7
KLK8 - kallikrein-related peptidase 8
KLK5 - kallikrein-related peptidase 5
KLK10 - kallikrein-related peptidase 10
|
The system has recognized 34072 genes out of 34101 gene terms entered by the user.
34072 genes were recognized by gene symbol and 0 genes by other gene IDs .
12595 duplicate genes were removed (keeping the highest ranking instance of each gene) leaving a total of 21477 genes
Only 17361 of these genes are associated with a GO term
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