GO Term |
Description |
P-value |
Enrichment (N, B, n, b) |
Genes |
GO:0016265 |
death |
9.29E-5 |
1.79 (17361,632,906,59) |
[+] Show genes
TMEM173 - transmembrane protein 173
ITGB2 - integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ACIN1 - apoptotic chromatin condensation inducer 1
TIAM2 - t-cell lymphoma invasion and metastasis 2
TRIM39 - tripartite motif-containing 39
KALRN - kalirin, rhogef kinase
LGALS12 - lectin, galactoside-binding, soluble, 12
C10orf2 - chromosome 10 open reading frame 2
CXCR4 - chemokine (c-x-c motif) receptor 4
CLN6 - ceroid-lipofuscinosis, neuronal 6, late infantile, variant
MECOM - mds1 and evi1 complex locus
BNIP3 - bcl2/adenovirus e1b 19kda interacting protein 3
NUP62 - nucleoporin 62kda
MCF2 - mcf.2 cell line derived transforming sequence
VDAC1 - voltage-dependent anion channel 1
FAS - fas (tnf receptor superfamily, member 6)
BMF - bcl2 modifying factor
AXIN1 - axin 1
NGFR - nerve growth factor receptor (tnfr superfamily, member 16)
AIFM1 - apoptosis-inducing factor, mitochondrion-associated, 1
NDOR1 - nadph dependent diflavin oxidoreductase 1
PANK2 - pantothenate kinase 2
NLRP1 - nlr family, pyrin domain containing 1
ITPR1 - inositol 1,4,5-triphosphate receptor, type 1
PAK2 - p21 protein (cdc42/rac)-activated kinase 2
ATXN3 - ataxin 3
TNFRSF18 - tumor necrosis factor receptor superfamily, member 18
BCL2L14 - bcl2-like 14 (apoptosis facilitator)
PLEKHG5 - pleckstrin homology domain containing, family g (with rhogef domain) member 5
CDKN2D - cyclin-dependent kinase inhibitor 2d (p19, inhibits cdk4)
IL1B - interleukin 1, beta
CLN3 - ceroid-lipofuscinosis, neuronal 3
CLN5 - ceroid-lipofuscinosis, neuronal 5
AFG3L2 - afg3 atpase family gene 3-like 2 (yeast)
TNFRSF1B - tumor necrosis factor receptor superfamily, member 1b
MTP18 - mitochondrial protein 18 kda
AKTIP - akt interacting protein
BAG5 - bcl2-associated athanogene 5
DDX41 - dead (asp-glu-ala-asp) box polypeptide 41
MAP1S - microtubule-associated protein 1s
BCL2L12 - bcl2-like 12 (proline rich)
EP300 - e1a binding protein p300
TM2D1 - tm2 domain containing 1
NEK6 - nima (never in mitosis gene a)-related kinase 6
BRCA1 - breast cancer 1, early onset
SPATA4 - spermatogenesis associated 4
CASP7 - caspase 7, apoptosis-related cysteine peptidase
TP53 - tumor protein p53
ATL1 - atlastin gtpase 1
RBM25 - rna binding motif protein 25
KIF5A - kinesin family member 5a
MAPK8 - mitogen-activated protein kinase 8
PTGER3 - prostaglandin e receptor 3 (subtype ep3)
WWOX - ww domain containing oxidoreductase
TNFRSF25 - tumor necrosis factor receptor superfamily, member 25
BRE - brain and reproductive organ-expressed (tnfrsf1a modulator)
BAG1 - bcl2-associated athanogene
API5 - apoptosis inhibitor 5
IER3 - immediate early response 3
|
GO:0008219 |
cell death |
1.26E-4 |
1.78 (17361,625,906,58) |
[+] Show genes
TMEM173 - transmembrane protein 173
ITGB2 - integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ACIN1 - apoptotic chromatin condensation inducer 1
TIAM2 - t-cell lymphoma invasion and metastasis 2
KALRN - kalirin, rhogef kinase
TRIM39 - tripartite motif-containing 39
LGALS12 - lectin, galactoside-binding, soluble, 12
C10orf2 - chromosome 10 open reading frame 2
CXCR4 - chemokine (c-x-c motif) receptor 4
CLN6 - ceroid-lipofuscinosis, neuronal 6, late infantile, variant
MECOM - mds1 and evi1 complex locus
BNIP3 - bcl2/adenovirus e1b 19kda interacting protein 3
NUP62 - nucleoporin 62kda
VDAC1 - voltage-dependent anion channel 1
MCF2 - mcf.2 cell line derived transforming sequence
FAS - fas (tnf receptor superfamily, member 6)
BMF - bcl2 modifying factor
AXIN1 - axin 1
NGFR - nerve growth factor receptor (tnfr superfamily, member 16)
NDOR1 - nadph dependent diflavin oxidoreductase 1
AIFM1 - apoptosis-inducing factor, mitochondrion-associated, 1
PANK2 - pantothenate kinase 2
NLRP1 - nlr family, pyrin domain containing 1
ITPR1 - inositol 1,4,5-triphosphate receptor, type 1
PAK2 - p21 protein (cdc42/rac)-activated kinase 2
ATXN3 - ataxin 3
TNFRSF18 - tumor necrosis factor receptor superfamily, member 18
BCL2L14 - bcl2-like 14 (apoptosis facilitator)
PLEKHG5 - pleckstrin homology domain containing, family g (with rhogef domain) member 5
CDKN2D - cyclin-dependent kinase inhibitor 2d (p19, inhibits cdk4)
IL1B - interleukin 1, beta
CLN3 - ceroid-lipofuscinosis, neuronal 3
CLN5 - ceroid-lipofuscinosis, neuronal 5
TNFRSF1B - tumor necrosis factor receptor superfamily, member 1b
MTP18 - mitochondrial protein 18 kda
AKTIP - akt interacting protein
BAG5 - bcl2-associated athanogene 5
DDX41 - dead (asp-glu-ala-asp) box polypeptide 41
BCL2L12 - bcl2-like 12 (proline rich)
MAP1S - microtubule-associated protein 1s
EP300 - e1a binding protein p300
TM2D1 - tm2 domain containing 1
NEK6 - nima (never in mitosis gene a)-related kinase 6
BRCA1 - breast cancer 1, early onset
SPATA4 - spermatogenesis associated 4
CASP7 - caspase 7, apoptosis-related cysteine peptidase
TP53 - tumor protein p53
ATL1 - atlastin gtpase 1
RBM25 - rna binding motif protein 25
KIF5A - kinesin family member 5a
MAPK8 - mitogen-activated protein kinase 8
PTGER3 - prostaglandin e receptor 3 (subtype ep3)
WWOX - ww domain containing oxidoreductase
TNFRSF25 - tumor necrosis factor receptor superfamily, member 25
BRE - brain and reproductive organ-expressed (tnfrsf1a modulator)
BAG1 - bcl2-associated athanogene
API5 - apoptosis inhibitor 5
IER3 - immediate early response 3
|
GO:0002675 |
positive regulation of acute inflammatory response |
4.15E-4 |
10.82 (17361,17,472,5) |
[+] Show genes
C3 - complement component 3
CNR1 - cannabinoid receptor 1 (brain)
TAC1 - tachykinin, precursor 1
IL1B - interleukin 1, beta
PTGER3 - prostaglandin e receptor 3 (subtype ep3)
|
GO:0032769 |
negative regulation of monooxygenase activity |
4.51E-4 |
9.47 (17361,11,833,5) |
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GLA - galactosidase, alpha
ENG - endoglin
GFI1 - growth factor independent 1 transcription repressor
CNR1 - cannabinoid receptor 1 (brain)
ARG2 - arginase, type ii
|
GO:0051001 |
negative regulation of nitric-oxide synthase activity |
5.93E-4 |
11.91 (17361,7,833,4) |
[+] Show genes
ENG - endoglin
GLA - galactosidase, alpha
CNR1 - cannabinoid receptor 1 (brain)
ARG2 - arginase, type ii
|
GO:0044092 |
negative regulation of molecular function |
6.04E-4 |
1.92 (17361,369,933,38) |
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GLA - galactosidase, alpha
ENG - endoglin
SSTR2 - somatostatin receptor 2
CDKN2A - cyclin-dependent kinase inhibitor 2a (melanoma, p16, inhibits cdk4)
LAX1 - lymphocyte transmembrane adaptor 1
GFI1 - growth factor independent 1 transcription repressor
CDKN2D - cyclin-dependent kinase inhibitor 2d (p19, inhibits cdk4)
PROX1 - prospero homeobox 1
PTPRC - protein tyrosine phosphatase, receptor type, c
IL1B - interleukin 1, beta
CLN3 - ceroid-lipofuscinosis, neuronal 3
SPRY4 - sprouty homolog 4 (drosophila)
BMP4 - bone morphogenetic protein 4
BAG5 - bcl2-associated athanogene 5
ADCY10 - adenylate cyclase 10 (soluble)
NF2 - neurofibromin 2 (merlin)
TNKS - tankyrase, trf1-interacting ankyrin-related adp-ribose polymerase
ARG2 - arginase, type ii
PSMD7 - proteasome (prosome, macropain) 26s subunit, non-atpase, 7
EGLN1 - egl nine homolog 1 (c. elegans)
NUP62 - nucleoporin 62kda
CSTA - cystatin a (stefin a)
IRAK1 - interleukin-1 receptor-associated kinase 1
RGS3 - regulator of g-protein signaling 3
CNR1 - cannabinoid receptor 1 (brain)
TP53 - tumor protein p53
PPP2CA - protein phosphatase 2 (formerly 2a), catalytic subunit, alpha isoform
FOXS1 - forkhead box s1
DBNDD2 - dysbindin (dystrobrevin binding protein 1) domain containing 2
SERPINE1 - serpin peptidase inhibitor, clade e (nexin, plasminogen activator inhibitor type 1), member 1
ARRB2 - arrestin, beta 2
NPY2R - neuropeptide y receptor y2
MDFI - myod family inhibitor
STIM2 - stromal interaction molecule 2
TNNT2 - troponin t type 2 (cardiac)
PAK2 - p21 protein (cdc42/rac)-activated kinase 2
SPRY1 - sprouty homolog 1, antagonist of fgf signaling (drosophila)
SORT1 - sortilin 1
|
GO:0006196 |
AMP catabolic process |
7.99E-4 |
2,170.12 (17361,2,4,1) |
[+] Show genes
AMPD3 - adenosine monophosphate deaminase (isoform e)
|
GO:0009128 |
purine nucleoside monophosphate catabolic process |
7.99E-4 |
2,170.12 (17361,2,4,1) |
[+] Show genes
AMPD3 - adenosine monophosphate deaminase (isoform e)
|
GO:0009169 |
purine ribonucleoside monophosphate catabolic process |
7.99E-4 |
2,170.12 (17361,2,4,1) |
[+] Show genes
AMPD3 - adenosine monophosphate deaminase (isoform e)
|
GO:0009158 |
ribonucleoside monophosphate catabolic process |
7.99E-4 |
2,170.12 (17361,2,4,1) |
[+] Show genes
AMPD3 - adenosine monophosphate deaminase (isoform e)
|
GO:0046968 |
peptide antigen transport |
8.15E-4 |
14.38 (17361,3,1207,3) |
[+] Show genes
CLEC4M - c-type lectin domain family 4, member m
CD209 - cd209 molecule
TAP2 - transporter 2, atp-binding cassette, sub-family b (mdr/tap)
|
GO:0008033 |
tRNA processing |
8.21E-4 |
2.51 (17361,77,1793,20) |
[+] Show genes
FDXACB1 - ferredoxin-fold anticodon binding domain containing 1
KARS - lysyl-trna synthetase
METTL1 - methyltransferase like 1
TRPT1 - trna phosphotransferase 1
PUS1 - pseudouridylate synthase 1
LSM6 - lsm6 homolog, u6 small nuclear rna associated (s. cerevisiae)
TRMT1 - trm1 trna methyltransferase 1 homolog (s. cerevisiae)
DUS3L - dihydrouridine synthase 3-like (s. cerevisiae)
CLP1 - clp1, cleavage and polyadenylation factor i subunit, homolog (s. cerevisiae)
TSEN2 - trna splicing endonuclease 2 homolog (s. cerevisiae)
POP5 - processing of precursor 5, ribonuclease p/mrp subunit (s. cerevisiae)
MTO1 - mitochondrial translation optimization 1 homolog (s. cerevisiae)
SSB - sjogren syndrome antigen b (autoantigen la)
ADAT3 - adenosine deaminase, trna-specific 3, tad3 homolog (s. cerevisiae)
TRMT6 - trna methyltransferase 6 homolog (s. cerevisiae)
HSD17B10 - hydroxysteroid (17-beta) dehydrogenase 10
TRDMT1 - trna aspartic acid methyltransferase 1
C4orf23 - chromosome 4 open reading frame 23
PUS7L - pseudouridylate synthase 7 homolog (s. cerevisiae)-like
THG1L - trna-histidine guanylyltransferase 1-like (s. cerevisiae)
|
GO:0043069 |
negative regulation of programmed cell death |
8.25E-4 |
1.81 (17361,376,1069,42) |
[+] Show genes
IL4 - interleukin 4
TDGF1 - teratocarcinoma-derived growth factor 1
PAX7 - paired box 7
CDKN2D - cyclin-dependent kinase inhibitor 2d (p19, inhibits cdk4)
DHRS2 - dehydrogenase/reductase (sdr family) member 2
IL1B - interleukin 1, beta
CLN3 - ceroid-lipofuscinosis, neuronal 3
TP63 - tumor protein p63
CD74 - cd74 molecule, major histocompatibility complex, class ii invariant chain
ESR1 - estrogen receptor 1
BMP4 - bone morphogenetic protein 4
FNTA - farnesyltransferase, caax box, alpha
TXNDC5 - thioredoxin domain containing 5 (endoplasmic reticulum)
MECOM - mds1 and evi1 complex locus
BNIP3 - bcl2/adenovirus e1b 19kda interacting protein 3
NUP62 - nucleoporin 62kda
ASCL1 - achaete-scute complex homolog 1 (drosophila)
SPHK1 - sphingosine kinase 1
IRAK1 - interleukin-1 receptor-associated kinase 1
NUAK2 - nuak family, snf1-like kinase, 2
CNTF - ciliary neurotrophic factor
FAS - fas (tnf receptor superfamily, member 6)
TP53 - tumor protein p53
CRYAA - crystallin, alpha a
NGFR - nerve growth factor receptor (tnfr superfamily, member 16)
TNFSF18 - tumor necrosis factor (ligand) superfamily, member 18
MAPK8 - mitogen-activated protein kinase 8
RBPJ - recombination signal binding protein for immunoglobulin kappa j region
ERBB2 - v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
SERPINE1 - serpin peptidase inhibitor, clade e (nexin, plasminogen activator inhibitor type 1), member 1
BDNF - brain-derived neurotrophic factor
SERPINB2 - serpin peptidase inhibitor, clade b (ovalbumin), member 2
TERT - telomerase reverse transcriptase
ERCC5 - excision repair cross-complementing rodent repair deficiency, complementation group 5
MITF - microphthalmia-associated transcription factor
SORT1 - sortilin 1
BAG1 - bcl2-associated athanogene
API5 - apoptosis inhibitor 5
IER3 - immediate early response 3
TNFRSF18 - tumor necrosis factor receptor superfamily, member 18
PDCD10 - programmed cell death 10
PCGF2 - polycomb group ring finger 2
|
GO:0012501 |
programmed cell death |
9.32E-4 |
1.77 (17361,499,906,46) |
[+] Show genes
PLEKHG5 - pleckstrin homology domain containing, family g (with rhogef domain) member 5
CDKN2D - cyclin-dependent kinase inhibitor 2d (p19, inhibits cdk4)
IL1B - interleukin 1, beta
TMEM173 - transmembrane protein 173
ACIN1 - apoptotic chromatin condensation inducer 1
ITGB2 - integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
TNFRSF1B - tumor necrosis factor receptor superfamily, member 1b
MTP18 - mitochondrial protein 18 kda
TIAM2 - t-cell lymphoma invasion and metastasis 2
AKTIP - akt interacting protein
BAG5 - bcl2-associated athanogene 5
DDX41 - dead (asp-glu-ala-asp) box polypeptide 41
MAP1S - microtubule-associated protein 1s
BCL2L12 - bcl2-like 12 (proline rich)
TRIM39 - tripartite motif-containing 39
KALRN - kalirin, rhogef kinase
EP300 - e1a binding protein p300
TM2D1 - tm2 domain containing 1
LGALS12 - lectin, galactoside-binding, soluble, 12
CXCR4 - chemokine (c-x-c motif) receptor 4
MECOM - mds1 and evi1 complex locus
NEK6 - nima (never in mitosis gene a)-related kinase 6
BNIP3 - bcl2/adenovirus e1b 19kda interacting protein 3
BRCA1 - breast cancer 1, early onset
SPATA4 - spermatogenesis associated 4
VDAC1 - voltage-dependent anion channel 1
MCF2 - mcf.2 cell line derived transforming sequence
CASP7 - caspase 7, apoptosis-related cysteine peptidase
FAS - fas (tnf receptor superfamily, member 6)
TP53 - tumor protein p53
BMF - bcl2 modifying factor
AXIN1 - axin 1
NGFR - nerve growth factor receptor (tnfr superfamily, member 16)
RBM25 - rna binding motif protein 25
AIFM1 - apoptosis-inducing factor, mitochondrion-associated, 1
MAPK8 - mitogen-activated protein kinase 8
WWOX - ww domain containing oxidoreductase
NLRP1 - nlr family, pyrin domain containing 1
PAK2 - p21 protein (cdc42/rac)-activated kinase 2
TNFRSF25 - tumor necrosis factor receptor superfamily, member 25
BRE - brain and reproductive organ-expressed (tnfrsf1a modulator)
BAG1 - bcl2-associated athanogene
API5 - apoptosis inhibitor 5
IER3 - immediate early response 3
TNFRSF18 - tumor necrosis factor receptor superfamily, member 18
BCL2L14 - bcl2-like 14 (apoptosis facilitator)
|
GO:0051259 |
protein oligomerization |
9.44E-4 |
1.83 (17361,189,1857,37) |
[+] Show genes
USP16 - ubiquitin specific peptidase 16
OLFM1 - olfactomedin 1
ATG16L1 - atg16 autophagy related 16-like 1 (s. cerevisiae)
BLM - bloom syndrome, recq helicase-like
TP63 - tumor protein p63
TGM3 - transglutaminase 3 (e polypeptide, protein-glutamine-gamma-glutamyltransferase)
PRNP - prion protein
PDSS2 - prenyl (decaprenyl) diphosphate synthase, subunit 2
C1QTNF7 - c1q and tumor necrosis factor related protein 7
OTC - ornithine carbamoyltransferase
HSD17B10 - hydroxysteroid (17-beta) dehydrogenase 10
MTMR2 - myotubularin related protein 2
NBR1 - neighbor of brca1 gene 1
GLRB - glycine receptor, beta
C10orf2 - chromosome 10 open reading frame 2
VCP - valosin-containing protein
IRAK1 - interleukin-1 receptor-associated kinase 1
UPK1A - uroplakin 1a
CNTF - ciliary neurotrophic factor
TRIM6 - tripartite motif-containing 6
TP53 - tumor protein p53
MALT1 - mucosa associated lymphoid tissue lymphoma translocation gene 1
ATL1 - atlastin gtpase 1
CRYAA - crystallin, alpha a
SEPT9 - septin 9
INSR - insulin receptor
DGKD - diacylglycerol kinase, delta 130kda
CDA - cytidine deaminase
MAP2K1 - mitogen-activated protein kinase kinase 1
TRIM4 - tripartite motif-containing 4
TEK - tek tyrosine kinase, endothelial
KCNMA1 - potassium large conductance calcium-activated channel, subfamily m, alpha member 1
TAF10 - taf10 rna polymerase ii, tata box binding protein (tbp)-associated factor, 30kda
SEPT7 - septin 7
CRYZ - crystallin, zeta (quinone reductase)
QPRT - quinolinate phosphoribosyltransferase
ALDH5A1 - aldehyde dehydrogenase 5 family, member a1
|
The system has recognized 34038 genes out of 34067 gene terms entered by the user.
34038 genes were recognized by gene symbol and 0 genes by other gene IDs .
12561 duplicate genes were removed (keeping the highest ranking instance of each gene) leaving a total of 21477 genes
Only 17361 of these genes are associated with a GO term
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